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Geoffrey Beene Gives Back

All net profits from Geoffrey Beene, LLC together with the Geoffrey Beene Foundation fund philanthropic causes that support initial-stage, out-of-the-box revolutionary research for treatments and prevention across all cancers as well as awareness and research for Alzheimer's, heart disease, scholarships, programs for veterans, protection of women and children and protection of animals.

GEOFFREY BEENE CANCER RESEARCH CENTER AT MEMORIAL SLOAN-KETTERING CANCER CENTER

A Look Inside the Geoffrey Beene Cancer Research Center

The GEOFFREY BEENE CANCER RESEARCH CENTER AT MEMORIAL SLOAN-KETTERING CANCER CENTER was established in 2006. The total value in combined funding to date from Geoffrey Beene is $138,000,000.

G. Thompson Hutton, the Trustee of the Geoffrey Beene Foundation and President of Geoffrey Beene, LLC, has orchestrated the activities to build and support this ambitious research initiative. "The hallmark of the GEOFFREY BEENE CANCER RESEARCH CENTER AT MEMORIAL SLOAN-KETTERING CANCER CENTER is its focus on revolutionary new research approaches across a variety of cancers, strategies that will lead to prevention through improved diagnostics and enhanced quality of life treatments toward the ultimate goal of making cancer a more manageable and perhaps one day, a curable disease."

Since its creation, the Geoffrey Beene Cancer Research Center has served as the focal point for an array of projects, aimed at translating works at the cellular level into revolutionary new research approaches to preventing, diagnosing, and treating the disease. It brings together researchers and physicians from two complementary areas: the Cancer Biology and Genetics Program, based in the Sloan-Kettering Institute (SKI), which studies the genetic and biochemical events that trigger the transformation of normal cells into cancerous ones, and the Memorial Hospital-based Human Oncology and Pathogenesis Program, which pursues new insights into the molecular mechanisms of cancer from the perspective of clinical oncology.

"The Geoffrey Beene Cancer Research Center has helped galvanize our efforts to gain new insights into cancer and to apply that knowledge to the development of more effective strategies for patient care," said Harold Varmus, former President of Memorial Sloan-Kettering Cancer Center, and now Director of the National Cancer Institute. "We are especially grateful to Tom Hutton and his colleagues at Geoffrey Beene, LLC for recognizing the significance of the work being done here."

The funds from Geoffrey Beene support advanced new research initiatives spanning the entire range of translational research, funding core research labs, research projects, the establishment of senior and junior faculty chairs, graduate fellowships, the annual Geoffrey Beene Symposium, and the annual Geoffrey Beene Research Retreat.

The Center provides support for the Geoffrey Beene Translational Oncology Core, directed by Dr. Charles Sawyers. The core performs genomic analyses of clinical material by applying state of the art genome-scale molecular profiling technologies. Geoffrey Beene salutes Dr. Sawyers for the extraordinary accomplishment of winning the prestigious 2009 Lasker-DeBakey Clinical Medical Research Award. His award is based on the development of molecularly-targeted treatments for chronic myeloid leukemia, converting a fatal cancer into a manageable chronic condition.

The Center also provides support for the Microchemistry and Proteomics Core Facility and Genomics Core Facility, both of which are aimed at significantly augmenting Memorial Sloan-Kettering's capacity for translational cancer research in genomics.

Since 2006, 74 grants have been awarded and 10 proposals for shared resources have been funded. Each grant funds initial-stage research and is renewed for a second year. Each year the Geoffrey Beene Cancer Research Center's Executive Committee reviews submissions of innovative research proposals. This highly competitive review process awards grants to the most compelling and profound ideas proposed by researchers from the Memorial Sloan-Kettering Cancer Center community. After completion of the funded project, grant recipients have gone on to develop their novel ideas and apply for further grants from external sources. Since 2007, for every dollar of direct support from the Geoffrey Beene Cancer Research Center, grant awardees received an additional $1.64 in follow-up funding from external sources based on the early-stage ideas supported by the Geoffrey Beene Cancer Research Center.

Scott Lowe, PhD, Member in the Cancer Biology and Genetics Program serves as Senior Chair. David Solit, M.D., Director of the Center for Molecular Oncology and Associate Member in Human Oncology and Pathogenesis Program was appointed to a Geoffrey Beene Senior Chair in 2013. Ping Chi, MD, PhD, Assistant Member in Human Oncology and Pathogenesis Program and Kitai Kim, PhD, Assistant Member Cancer Biology and Genetics Program are currently appointed Geoffrey Beene Junior Faculty Chairs. Andrea Ventura, MD, PhD, Assistant Member in the Cancer Biology and Genetics Program, and Johanna Joyce, PhD and Ross Levine, MD, Assistant Members in the Human Oncology and Pathogenesis Program have previously held the Geoffrey Beene Junior Faculty Chairs. Since the establishment of the Geoffrey Beene Cancer Research Center, 22 Geoffrey Beene Graduate Fellowships have been awarded. Hyung-Song Nam, an MD, PhD student, and Sindy Escobar-Alvarez, a PhD student, were named the first Geoffrey Beene graduate fellows in 2007. The second Geoffrey Beene Graduate Fellowships in 2008 were awarded to two PhD students, Vasilena Gocheva and Barry S. Taylor. In 2009, the third Geoffrey Beene Graduate Fellowships were awarded to three PhD students, Neha Bhagwat, John Holliday, and Ellen Hukkelhoven. In 2010, three Geoffrey Beene Graduate Fellowships were awarded to PhD students, Piero Sanfilippo, Daniel Marks and Oakley Olson. In 2011, three Geoffrey Beene Graduate Fellowships were awarded to PhD students, Robert Bowman, Jenny Karo and Gregory Mazo. In 2012, three Geoffrey Beene Graduate Fellowships were awarded to PhD students, Emily Casey, Neel Shah and Edward Kastenbhuber. We are proud to announce that in 2013 three Geoffrey Beene Graduate Fellowships were awarded to PhD students Kinsha Gala, Mary Klein and Kelsey Temprine.

Oversight of the GEOFFREY BEENE CANCER RESEARCH CENTER is provided by the following members of its Executive Committee:

Scott Lowe, PhD

Chair, Geoffrey Beene Cancer Research Center

Craig Thompson, MD

President, Memorial Sloan-Kettering Cancer Center

Alexandra Rudensky, PhD

Chair, Immunology Program

Joan Massagué, PhD

Director, Sloan Kettering Institute

Larry Norton, MD

Deputy Physician-in-Chief, Breast Cancer Programs

Charles Sawyers, MD

Chair, Human Oncology and Pathogenesis Program

David Scheinberg, MD, PhD

Chair, Molecular Pharmacology and Chemistry Program

Scott A. Armstrong, MD, PhD

Member, Human Oncology and Pathogenesis Program

Josť Baselga, MD, PhD

Physician-in-Chief, Memorial Hospital

G. Thompson Hutton
Ex Officio

Trustee of the Geoffrey Beene Foundation and
President of Geoffrey Beene, LLC.